Jimmy Fallon and Jamie Lee Curtis Transform Into Nathan Fielder and Elizabeth Holmes to Spoof ‘You Can See Everything’

On Wednesday night’s episode of “The Tonight Show,” host Jimmy Fallon went full Nathan Fielder while guest Jamie Lee Curtis played Elizabeth Holmes to spoof A24’s buzzy documentary, “You Can See Everything.”

“Now, be honest. Do you really want to be on the show tonight?” asks Fallon, doing his best Fielder impression. “Of course I do. I love talking to you,” responded Curtis with her best Holmes-like voice while donning a blonde wig and looking deeply into the late-night host’s eyes. “So, you’re not just here to promote your new show. ‘Newlyweds’?” “No, I’m engaging with you as a human being,” said Curtis. “Why would I deceive you? There’s no reason for me to do that. There’s nothing for me to deceive you on.”

“Good chat,” concluded Fallon, but not before one last question: “You’re being real right now?” “I’m always being real,” responded Curtis. As Fallon leaves, she yells, “Thank God! Fuck, what an asshole!”

As mentioned in the cold open, Curtis was on the show to promote “Newlyweds,” her new NBC sitcom that premiered on Oct. 23. The logline for the show, starring Téa Leoni and Tim Daly, describes it as “a later-in-life love story about a free-spirited woman and a buttoned-up professor who marry impetuously after a whirlwind courtship.”

Curtis will appear on the show in a recurring guest star role, and also co-created it with Gail Lerner, who was fired from the show earlier this month for “creative differences.” In Lerner’s statement when the news broke, she described the experience working on the show as “the most joyous TV experience of my life.”

“You Can See Everything,” which debuted in theaters earlier this month on Oct. 16, has been a hit both critically and at the box office, where it’s already grossed $45.1 million domestically to date. Fielder and co-director Lance Oppenheim quietly worked on the movie for more than three years, which offers an unhinged look at the Theranos founder a month before she began an 11-year prison sentence for defrauding investors.

Watch the full cold open here.